nanobio

 



Biocompatibility of nanomaterials


  • Surface modification of gold nanorods and its effect on inflammatory response in macrophage cells

gold_particles

We investigated the effects of different surface modifications and concentrations of GNRs on inflammatory cytokine induction in murine macrophage Raw264.7 cells. The release of two inflammatory cytokines (interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α)) were investigated in this study because they are strongly associated in sepsis syndrome and other immune diseases.
For more details, please go to http://onlinelibrary.wiley.com/doi/10.1002/ppsc.201200115/abstract

  • Cytotoxicity of RAFT Polymers

The reversible addition-fragmentation chain transfer (RAFT technique) has been increasingly used to generate polymers for potential biological applications. However, the toxicity of the RAFT-polymers has received limited attention. In this study, the in vitro cytotoxicity of three different, RAFT-synthesized, water-soluble polymers was investigated using three different adherent cell lines via CellTiter-Blue cell viability and the cytosolic enzyme lactate dehydrogenase (LDH) cytotoxicity assays.
For more details, please go to http://pubs.acs.org/doi/abs/10.1021/bm901129x

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